T细胞表达Ig可变区基因的假说,曾在一些研究者中产生了一种乐观的情绪,认为T细胞抗原受体很快就会搞清楚了。目前,由于受分子生物学的冲击,看来既打破了这个假说,也清除了这种乐观的情绪。此假说曾证明是正确的吗? T细胞表达Ig可变区基因的证据是来自于用抗Ig分子的抗血清所进行的研究,这些抗血清是检测独特型决定基的,及在某些情况下是检测V_H骨架决定基的。曾证明具有各种特异性的T细胞和具有各种效应功能的 The hypothesis that T cells express the Ig variable region gene has generated an optimistic mood among some researchers that T cell antigen receptors will soon be clear. At present, due to the impact of molecular biology, it seems to break this hypothesis, but also clear this optimism. Has this hypothesis been proven to be correct? The evidence for T-cells expressing the Ig variable region genes comes from studies with antisera raised against anti-Ig molecules that are used to detect idiotypic determinants, and in some cases The next step is to detect the V_H skeleton determinant. Has demonstrated various specificity of T cells and has a variety of effector functions