应用外周血淋巴细胞培养G显带技术 ,对 15 6 1例患者进行细胞遗传学检查 ,检出异常染色体 2 5 2例 ,其中Y染色体异常 96例 ,均有不同程度的临床效应 ,包括 8种细胞核型。对这些核型及其与疾病的关系进行分析讨论。其中Y染色体异常大部分表现为胎儿丢失和有畸形儿生育史。大Y与生育异常的关系一直有争论。作者认为 ,大Y与生育异常有关。 Using peripheral blood lymphocyte culture G-banding technique, 1561 cases of cytogenetic examination showed 252 cases of abnormal chromosomes, including Y chromosome abnormalities in 96 cases, with varying degrees of clinical effect, including 8 kinds Karyotype. The relationship between these karyotypes and their diseases is analyzed and discussed. Y chromosome abnormalities in which most of the performance of the fetus lost and deformed children fertility history. The relationship between large Y and fertility abnormalities has been controversial. The author believes that large Y and fertility abnormalities.