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目的探讨前列腺增生(BPH)CT灌注成像的价值。资料与方法将62例BPH患者作为研究组,按超声分级标准分为BPHⅠ21例,BPHⅡ16例,BPHⅢ25例。另选30名健康志愿者为正常组。对两组受检者行前列腺中心层面灌注扫描,得到正常前列腺及各级别BPH组织灌注(PF)图、强化峰值(PEI)图、达峰时间(TTP)图、血容量(BV)值和时间-密度曲线(TDC)。采用单因素方差分析和q检验,对正常组和研究组各级别BPH组织灌注值进行对比分析。结果PF值,BPH各级别均>正常组,差异均有统计学意义(P<0.05);PEI值,BPHⅠ组>正常组,但差异无统计学意义(P>0.05),BPHⅢ、BPHⅡ均>正常组,差异有统计学意义(P<0.05);TTP值,正常组>BPH各级别组,差异无统计学意义(P>0.05);BV值,两组差异均有统计学意义(P<0.05)。结论BPH组织较正常前列腺呈高血流灌注,但CT灌注不能区分正常前列腺与BPHⅠ级,亦无法对BPH分级。
Objective To investigate the value of CT perfusion imaging in benign prostatic hyperplasia (BPH). Materials and Methods 62 cases of BPH patients as the study group, according to the ultrasonic grading standards were divided into BPH Ⅰ 21 cases, BPH Ⅱ 16 cases, BPH Ⅲ 25 cases. Another 30 healthy volunteers were selected as normal group. Peripheral prostatic heart perfusion scanning was performed on the two groups of subjects to obtain the normal prostate and all levels of BPH tissue perfusion (PF), PEI, TTP, BV and time - Density curve (TDC). One-way analysis of variance and q test were used to compare the perfusion values of BPH tissue between the normal group and the study group. Results The levels of PF and BPH were all higher than those in the normal group (P <0.05), while the values of PEI and BPHⅠwere no difference (P> 0.05) (P <0.05). There was no significant difference between TTP value and normal group (P> 0.05). There was significant difference between the two groups (P < 0.05). Conclusion BPH tissue is more perfusion than normal prostate, but CT perfusion can not differentiate normal prostate from BPH grade Ⅰ, nor can it grade BPH.