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为探讨渗出型老年黄斑变性（ＡＭＤ）的病灶损害和视功能改变的发展特征，用视力、眼底彩照和荧光血管造影（ＦＦＡ）、明视视网膜电图（ＥＲＧ）、ＦＭ１００—ｈｕｅ色彩试验分别对４８只、２４只、３５只及１４只渗出型ＡＭＤ患眼进行了随访检测。结果：渗出型ＡＭＤ的病灶损害发展快慢不一，但６５岁以上组，其病灶发展速率比６５岁以下组的要快些（Ｐ＜０．０５）。在平均３３．２个月的随访过程中，有７５．０％的患眼随访终了时的视力在０．１或以下。明视ＥＲＧ和ＦＭ１００—ｈｕｅ色彩试验在随访前后无明显变化。结论：６５岁以上的渗出型ＡＭＤ患者，其病灶损害一般发展较快，大部分患眼在随访终了时视力在０．１或以下。
To investigate the developmental features of focal lesion and visual function in patients with exudative AMD, FFA, ERG and FM100-hue color tests were performed respectively 48, 24, 35 and 14 exudative AMD patients were followed up. Results: The development of exudative AMD lesion progressed slowly, but the rate of lesion development in patients over 65 years old was faster than that of 65 years old group (P <0.05). During an average of 33.2 months of follow-up, 75.0% of patients had visual acuity of 0.1 or less at the end of follow-up. Clear vision ERG and FM100-hue color test before and after follow-up no significant change. CONCLUSIONS: Exudative AMD patients older than 65 develop lesion lesions generally faster, and most have a visual acuity of 0.1 or less at the end of follow-up.