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目的通过显微CT体外评价,比较3种不同直径羟磷灰石颗粒外部间隙分布情况,探讨材料外部间隙对临床运用的影响。方法 2014年3—4月于广州科学城显微CT实验室对颗粒直径分别为0.25~1 mm、0.4~1 mm、1~2 mm的3种人工骨材料进行体外固定,采用显微CT扫描,评价各自的间隙排列。结果 1~2 mm组羟基磷灰石颗粒压实堆积后显微CT下显示材料颗粒排列松散,颗粒团块间存在较大空隙,间隙率为61.75%;0.25~1 mm和0.4~1 mm组材料颗粒排列较为均匀,颗粒团块间存在间隙较小,间隙率分别为27.33%和42.44%。结论显微CT可用于颗粒移植材料的微观物理参数评估,0.25~1 mm组羟磷灰石颗粒压实后颗粒团块内部排列紧密,临床上有利于植骨后稳定成骨空间。
OBJECTIVE: To evaluate the effect of material gap on the clinical application of micro-CT in vitro by comparing the distribution of external gaps of three kinds of hydroxyapatite particles with different diameters. Methods From March to April 2014, three artificial bone materials with diameters of 0.25 ~ 1 mm, 0.4 ~ 1 mm and 1 ~ 2 mm respectively were fixed in the Microscope CT Laboratory of Guangzhou Science City. , Evaluate the gap arrangement. Results The microstructure of the hydroxyapatite particles compacted in 1 ~ 2 mm group showed that the material particles were loosely arranged and the gaps between the particles were 61.75%, 0.25 ~ 1 mm and 0.4 ~ 1 mm The particles of the material are arranged more evenly, the gaps between the particles are smaller, and the gaps are 27.33% and 42.44% respectively. Conclusion Micro-CT can be used to evaluate the microscopic physical parameters of the grafted material. The 0.25-1 mm group of hydroxyapatite particles are compactly arranged inside the agglomerates and are clinically beneficial to stabilize the osteogenic space after bone grafting.