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目的总结分析甲状腺Hürthle细胞肿瘤诊治经验。方法回顾性分析东南大学附属中大医院2002-2006年收治的15例甲状腺Hürthle细胞肿瘤的临床病理资料。结果病人均以发现颈部包块就诊。女性14例。术前甲状腺功能检查均正常,B超、ECT无法确诊,细针穿刺发现Hürthle细胞。术中快速冰冻均能确诊。15例中,13例为良性,其中8例行腺叶切除加峡部切除,3例单纯腺叶切除,2例合并甲状腺乳头状癌而行根治术;2例为恶性,均行根治手术。术后随访无复发。结论应充分认识甲状腺Hürthle细胞肿瘤,重视细针穿刺细胞学检查。术中冰冻切片检查对诊断很重要。选择合适的手术方式可使病人获得良好的预后。
Objective To summarize and analyze the diagnosis and treatment of thyroid Hürthle tumor. Methods The clinicopathological data of 15 cases of thyroid Hürthle cell tumors admitted to the Affiliated Zhongda Hospital of Southeast University during 2002-2006 were retrospectively analyzed. Results Patients were found to find the neck mass. 14 females. Preoperative thyroid function tests were normal, B ultrasound, ECT can not be diagnosed, fine needle aspiration Hürthle cells. Intraoperative rapid freezing can be diagnosed. Of the 15 cases, 13 were benign, including 8 underwent lobectomy with isthmus resection, 3 underwent simple lobectomy and 2 underwent papillary thyroidectomy. 2 were malignant and underwent radical surgery. No recurrence after surgery. Conclusion Thyroid Hürthle tumor should be fully understood, and fine needle aspiration cytology should be emphasized. Intraoperative frozen section examination is very important for diagnosis. Select the appropriate surgical approach allows patients to get a good prognosis.