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[目的]筛选肺癌患者术后呼吸功能衰竭的术前心理、肺功能等相关危险因素。[方法]采用病例对照研究分析病例组和对照组肺癌患者术前肺功能相关指标以及焦虑自评量表(SAS)与抑郁自评量表(SDS)评分,通过单因素和多因素分析进行危险因素筛选。[结果]多因素Logistic回归分析显示肺一氧化碳弥散量、最大呼气中段流量、1秒用力呼气容积以及25%肺活量最大呼气流量异常和术前抑郁是术后呼吸功能衰竭的危险因素。[结论]肺癌患者术前肺功能低和术前抑郁可能是术后呼吸功能衰竭的高危因素。
[Objective] To screen the preoperative psychology, lung function and other related risk factors of postoperative respiratory failure in patients with lung cancer. [Methods] A case-control study was conducted to analyze the preoperative pulmonary function-related indicators and self-rating anxiety scale (SAS) and self-rating depression scale (SDS) scores of patients with lung cancer in case group and control group by single factor and multivariate analysis Factor screening. [Results] Multivariate logistic regression analysis showed that carbon monoxide diffusion, maximum expiratory flow, forced expiratory volume per second, and maximum expiratory flow rate of 25% vital capacity and preoperative depression were the risk factors of postoperative respiratory failure. [Conclusions] Preoperative lung function and preoperative depression in patients with lung cancer may be the risk factors of postoperative respiratory failure.