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采用放射免疫测定法,测定了52例恶性血液病患者血清铁蛋白(SF)水平改变,并与正常组及恶性实体瘤组比较,发现观察组化疗前血清SF水平明显高于正常对照组(p<0.01)及恶性实体瘤组(p<0.05)部分化疗后达缓解或部分缓解的恶性血液病患者血清SF水平明显减低 结论:血清SF测定可作为恶性血液病患者急性期或活动期观察指标
Radioimmunoassay was used to determine the changes of serum ferritin (SF) levels in 52 patients with hematological malignancies. Compared with normal and malignant solid tumors, the serum SF levels in the observation group before treatment were significantly higher than those in the normal control group (p <0.01) and malignant solid tumors (p<0.05) Serum SF levels were significantly reduced in patients with hematologic malignancies who achieved remission or partial remission after partial chemotherapy Conclusion: Serum SF determination can be used as an indicator of acute or active hematological malignancy