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A method,which was a modification of that of Stothert et al,was adopted to establish chronic lung lymph fistula in goats fromChongqing area.The procedure consisted mainly that a segment ofthe thoracic duct was isolated to serve as the efferent of the caudalmediastinal lymph node to collect lung lymph,and an irrigationtube was inserted for the periodic administration of heparin solutionto prevent the sanguinous lymph from clotting in the early post-operative days.A series of difficulties including high surgical morta-lity,stoppage of lymph flow,and chyle contamination of the lunglymph were overcome.A trial of the operated goats on steaminhalation injury precipitated instant increase of lung lymph flowand an elevation of lymph/plasma ratio of total protein concentration,which suggested that our animal model was suitable and effective inthe study of the exchanges of fluid and protein in the lungs.Thedetails of technique were described and discussed.
A method, which was a modification of that of Stothert et al, was adopted to establish chronic lung lymph fistula in goats from Central area. The procedure consisted primarily that a segment of the thoracic duct was isolated to serve as the efferent of the caudal mediastinal lymph node to collect lung lymph, and an irrigationtube was inserted for the periodic administration of heparin solutionto prevent the sanguinous lymph from clotting in the early post-operative days. A series of conflicts including high surgical morta-lity, stoppage of lymph flow, and chyle contamination of the lunglymph were overcome. A trial of the operated goats on steaminhalation injury precipitated instant increase of lung lymph flowand an elevation of lymph / plasma ratio of total protein concentration, which suggested that our animal model was suitable and effective inthe study of the exchanges of fluid and protein in the lungs. The details of technique were described and discussed.