【摘 要】
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Over the past two decades, layer-by-layer (LbL) assembly of micro/nanocapsules has been of interest for the investigation of bio-nano interactions to explore bi
【机 构】
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Key Laboratory of Colloid and Interface Chemistry of the Ministry of Education, School of Chemistry
论文部分内容阅读
Over the past two decades, layer-by-layer (LbL) assembly of micro/nanocapsules has been of interest for the investigation of bio-nano interactions to explore bio-applications, such as drug delivery. The choice of an appropriate template that can be easily dissolved under mild conditions is one of the challenges for the assembly of LbL capsules. Herein, we report the engineering of LbL capsules with tunable morphologies using cuprous oxide (Cu2O) particles as templates. Cu2O particles with cubic, tetradecahedral or spherical morphologies were synthesized via hydrothermal processes, which can be dissolved under mild condition (e.g., sodium thiosulfate solution). The influence of capsule morphologies on cell association was investigated, which indicates that LbL capsules with cubic geometry promoted cell association up to 4 and 9-fold than tetradecahedral and spherical capsules, respectively. The reported method provides a new avenue for the assembly of LbL capsules with different morphologies, which has the potential for better understanding of biological interactions of LbL capsules.
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