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来自于美国得克萨斯大学西南医学中心的研究人员在果蝇中发现一个可同时限制细胞增殖并促进细胞死亡的肿瘤抑制基因;该基因有可能在人类癌发生过程中发挥重要作用。敲除 hippo 基因,结果将导致肿瘤在果蝇体内的每一个器官上形成。该研究发现已在近期的《细胞》杂志网络版上发表。
Researchers from the University of Texas Southwestern Medical Center in the United States discovered a tumor suppressor gene in Drosophila that simultaneously inhibits cell proliferation and promotes cell death; it may have an important role in the development of human cancers. Knockout of the hippo gene results in tumors forming on every organ in the flies. The findings were published in a recent online edition of The Cell magazine.