胰岛素为胰腺激素肽,经胃肠道(主要是在上部),可受蛋白水解而失活,而且本身又易结合成高分子量的低聚物,故口服胰岛素无效。糖尿病人经肠道外给药的疗效亦有差异,因而需要继续寻找胰岛素的有效给药途径。作者前曾用非离子表面活性剂(Cetamacrogol Insulin is a pancreatic hormone peptide that, via the gastrointestinal tract (mainly in the upper part), can be proteolytically inactivated and itself easily incorporated into high molecular weight oligomers, so oral insulin is ineffective. There are also differences in the efficacy of parenteral administration of diabetes mellitus, so there is a continuing need to find an effective route of administration of insulin. The author used nonionic surfactant (Cetamacrogol