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目的:通过人群与虫媒监测,探索登革热疫情防控措施。方法:开展病例搜索,对可能感染者进行登革热IgM/IgG抗体检测,同时开展虫媒监测。结果:患者郑某发病后第9d登革热IgM抗体弱阳性,IgG抗体阴性,隔天复检,IgM/IgG抗体均为弱阳性,二周后检测,两抗体均呈强阳性,且IgM抗体呈4倍以上增长;血清标本病毒核酸荧光RT-PCR分型检测为登革Ⅲ型病毒。搜索病例11人和可能感染者67人,登革热IgM/IgG抗体检测结果均为阴性。患者曾就诊于多家医院,临床医生均未考虑登革热。虫媒监测38户,73个容器,4户9个容器有伊蚊或虫卵,布雷图指数(BI)为23.68,容器指数(CI)为12.33,房屋指数(HI)为10.53;应急灭蚊后监测评估,BI、CI和HI均为0.00。结论:患者可确诊为该县首例登革热病例;加强临床医生培训,探索传染源,加强常规监测,是防控登革热的关键措施。
Objective: To explore the prevention and control measures of dengue fever through population and insect monitoring. Methods: To carry out case search, detect possible IgM / IgG antibodies against possible infection and carry out vector monitoring. Results: The IgM antibody of Dengue was weakly positive on the 9th day after the onset of the disease, and the IgG antibody was negative. On the next day, the IgM / IgG antibody was weakly positive. After two weeks, the IgM antibody was strongly positive and IgM antibody was 4 Times more than the growth of the serum samples of viral nucleic acid fluorescence RT-PCR typing detection of dengue virus type III. 11 cases were searched and 67 were possibly infected. The results of dengue IgM / IgG antibody tests were negative. Patients have been to a number of hospitals, clinicians did not consider dengue fever. Insect vectors monitored 38 households with 73 containers, 4 households with 9 containers with Aedes aegypti or eggs, the Bret index (BI) of 23.68, the container index (CI) of 12.33 and the house index (HI) of 10.53; Post-monitoring assessment, BI, CI and HI were 0.00. Conclusion: Patients can be diagnosed as the first case of dengue fever in the county. Strengthening clinicians’ training, exploring source of infection and strengthening routine monitoring are the key measures to prevent and control dengue fever.