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对体外受精-胚胎移植(IVF-ET)和胞浆内单精子注射(ICSI)后原核形成情况进行常规检查可以判定和分离异常受精的合子,德国Rosenbusch等对ICSI后显示3个原核和1个极体的人类合子进行了细胞遗传学分析,试图阐明妊娠最早期染色体异常的频率与起源。
Routine examination of pronuclei after in vitro fertilization-embryo transfer (IVF-ET) and intracytoplasmic sperm injection (ICSI) can be used to determine and isolate abnormally fertilized zygotes. Rosenbusch et al. Showed 3 prokaryotic and 1 The polar body of human zygotes cytogenetic analysis, trying to clarify the earliest chromosomal abnormalities in pregnancy frequency and origin.