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环孢菌素A抑制了用ConA和PMA在体外诱导小鼠脾淋巴细胞分泌的白细胞介素2、白细胞介素3和粒细胞巨噬细胞集落刺激因子,这种抑制作用与这些淋巴因子的信使核糖核酸的基因表述受到抑制有关。
Cyclosporine A inhibits interleukin-2, interleukin-3, and granulocyte-macrophage colony-stimulating factor secretion induced by ConA and PMA in mouse splenic lymphocytes in vitro and this suppressive effect is associated with the messenger of these lymphokines Ribosomal gene expression is inhibited.