近十几年来,一个具有特定三叶结构且与粘糖蛋白相关的胃肠肽家族———三叶因子家族已得到确认。肠三叶因子(intestinal trefoil factor,ITF)为三叶肽家族成员之一,存在于多种哺乳动物组织中。与其他胃肠肽激素相同,ITF由肠道分泌后,一部分进入血液循环,一部分随粪便排出体外。 For more than a decade, a family of gastrointestinal peptides with a specific trilobal structure associated with the mucoprotein has been identified. Intestinal trefoil factor (ITF) is a member of the trefoil peptide family and is found in various mammalian tissues. As with other gastrointestinal peptide hormones, ITF is secreted by the gut and part of it enters the bloodstream and excretes some of it with the excrement.