脂肪抑制FSPGR序列:胰腺病变定量和定性分析的ROC曲线评价

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目的利用ROC曲线评价平扫脂肪抑制FSPGR序列检出胰腺疾病的准确性。方法对92例研究对象行脂肪抑制FSPGR序列扫描,其中57例正常胰腺,35例异常胰腺,测量RO I的信号强度,并计算胰腺相对于肝脏、脾脏的信号强度比值,然后进行定性评价。结果相对于肝脏或者脾脏的信号强度,正常和异常胰腺之间的相对信号强度存在差异。并且胰腺相对于肝脏、脾脏ROC曲线下的面积分别为0.92±0.03、0.91±0.04。与肝脏相比较,对胰腺的定量与定性评价无显著性差异,定性分析检出胰腺病变的敏感性为86.7%,特异性为91.2%。结论在鉴别正常和异常胰腺方面,定性判断与定量分析一样精确,且两者均能够检出胰腺的病变。 OBJECTIVE: To evaluate the accuracy of pancreatic diseases detected by plain fat suppression FSPGR sequence using ROC curve. Methods Forty-two subjects underwent FIPGR scan, 57 normal and 35 abnormal pancreas. The signal intensity of ROI was measured. The signal intensity ratio of the pancreas to liver and spleen was calculated, and then the qualitative evaluation was performed. Results There was a difference in relative signal intensity between normal and abnormal pancreas relative to the signal intensity of the liver or spleen. The areas under the ROC curve of the pancreas relative to the liver and spleen were 0.92 ± 0.03 and 0.91 ± 0.04, respectively. Compared with the liver, there was no significant difference between the quantitative and qualitative evaluation of the pancreas. The sensitivity and specificity of qualitative analysis of pancreatic lesions were 86.7% and 91.2% respectively. Conclusions Qualitative judgment is as accurate as quantification in identifying normal and abnormal pancreas, and both are capable of detecting pancreatic lesions.
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