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目的探讨丹参多酚酸盐联合常规治疗对脑梗死患者神经功能及脑血流动力学的影响。方法选取本院2014年2月—2015年10月收治的脑梗死患者90例,随机分成2组,每组45例。对照组进行常规治疗,观察组在对照组基础加用丹参多酚酸盐治疗。比较2组患者神经功能及脑血流动力学改善情况。结果观察组神经功能缺损程度评分明显低于对照组(P<0.05);观察组舒张末流量、最大峰值流速、血管阻力指数以及血管搏动指数明显高于对照组(P<0.05)。结论丹参多酚酸盐联合常规治疗能够有效改善脑梗死患者神经功能和脑血流动力学,缓解患者病情,提高患者生活质量,具有较高的临床应用价值。
Objective To investigate the effects of Salviae miltiorrhizae polyphenols combined with routine therapy on neurological function and cerebral hemodynamics in patients with cerebral infarction. Methods Ninety patients with cerebral infarction who were treated in our hospital from February 2014 to October 2015 were randomly divided into two groups (n = 45 in each group). Control group for conventional treatment, the observation group in the control group plus salvianolate treatment. The neurological function and hemodynamic improvement were compared between the two groups. Results The score of neurological impairment in observation group was significantly lower than that in control group (P <0.05). The end-diastolic flow rate, maximum peak velocity, vascular resistance index and vascular pulsatility index in observation group were significantly higher than those in control group (P <0.05). Conclusion Salviae miltiorrhizae polyphenols combined with conventional treatment can effectively improve the neurological function and cerebral hemodynamics in patients with cerebral infarction, relieve the patient’s condition and improve the quality of life of patients with high clinical value.