肝门胆管癌仍是胆管癌中较难治疗的一种类型 ,其手术切除后预后与淋巴结转移密切有关。传统的HE染色和病理技术常低估淋巴结微转移的发生率 ,应用细胞角蛋白抗体的免疫组化技术可检出传统病理学遗漏的微转移淋巴结 ,作者首次进行这方面研究。取日本Nagoya大学医院第一外科于 1 Hilar cholangiocarcinoma is still a type of cholangiocarcinoma more difficult to treat, and its prognosis after surgical resection is closely related to lymph node metastasis. Traditional HE staining and pathology often underestimate the incidence of micrometastases in lymph nodes. Using immunohistochemistry of cytokeratin antibodies to detect micrometastases missed by traditional pathology, the authors first conducted this study. Take the first surgery at Nagoya University Hospital in Japan