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目的:探讨近十年来胃癌临床病理特点的发展趋势.方法:以我院1994-2003年间经胃镜检查和病理证实的胃癌1765例为研究对象,分成1994-1998和1999-2003前后两组,探讨性别、年龄、部位、组织学类别的差异.结果:两组资料中男女之比较为接近分别为1组3.33:1,2组3.29:1.男性构成比均明显高于女性(P<0.05),但两组间差异无显著性.1765例患者40岁以下者795例(12.86%),40-60岁者227例(45.04%),60岁以上者227例(42.10%),两组内年龄在40岁以上的胃癌患者构成比均较高.与2组相比,1组40-60岁患者构成比高于2组(χ~2=6.116,P=0.013),而60岁以上患者比例低于2组(χ~2=4.983,P=0.026).两组患者发病部位均以胃体、胃窦及贲门处为最常见.相对于1组,2组胃癌发生于胃底处患者比例增多(χ~2=6.116,P=0.01),而发生于幽门处者比例减少(χ~2=6.116,P=0.007).两组胃癌患者常见组织类型都为低分化腺癌及中分化腺癌.结论:胃癌患者发病年龄上升,发生部位有向近端上移趋势.
Objective: To explore the clinicopathological features of gastric cancer in recent ten years.Methods: A total of 1765 cases of gastric cancer confirmed by gastroscopy and pathology from 1994 to 2003 in our hospital were divided into two groups before and after 1994-1998 and 1999-2003 Gender, age, location, histological classification.Results: The male and female of the two groups were close to 3.33: 1 group and 3.29: 1 respectively, the male constitutional ratio was significantly higher than that of female (P <0.05) , But there was no significant difference between the two groups.Among 1765 patients, 795 cases (12.86%) were below 40 years old, 227 cases (45.04%) were 40-60 years old and 227 cases (42.10%) were over 60 years old, The proportions of patients with gastric cancer over the age of 40 were higher than those of the two groups (P <0.05), while those in the group 40-60 were higher than those in the two groups (χ ~ 2 = 6.116, P = 0.013) The incidence of gastric cancer was the most common in the two groups (χ ~ 2 = 4.983, P = 0.026) .The incidence of gastric cancer was the most common in the two groups (Χ ~ 2 = 6.116, P = 0.01), while the proportion in patients with pylorus decreased (χ ~ 2 = 6.116, P = 0.007) .The common types of gastric cancer in both groups were poorly differentiated adenocarcinoma and moderately differentiated Adenocarcinoma. Conclusion: Gastric cancer patients The age of onset increases, the occurrence of the site to the proximal upward trend.