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用巢式PCR技术检测了50例不明原因自然流产胚胎组织中B19DNA，其中25例同时留取静脉血，另25例同时留取产道血送检；结果3种标本中均检出B19DNA，组织中检出率最高，差异无显著性；认为用胚胎组织和（或）产道血代替静脉血诊断胎儿B19感染有很多优点。
Nested PCR technique was used to detect B19 DNA in 50 cases of spontaneous abortion embryos of unknown origin, of which 25 cases received venous blood at the same time and the other 25 cases received birth canal blood tests. Results B19DNA was detected in all 3 specimens The detection rate was the highest with no significant difference. It was considered that there were many advantages in diagnosing fetal B19 infection by using fetal tissue and / or birth canal blood instead of venous blood.