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【《新英格兰医学杂志》1987年1月】已知初次妊娠发生较早,有保护机体日后不易患乳腺癌的作用。美国 Musey 等人推测,这种影响可能是通过妊娠后催乳素的分泌受到长期抑制而起作用的。为此,他们对初次妊娠在18～23岁的15名妇女和初次妊娠在29～40岁的9名扫女,在初次足月妊娠前后分别测定了血清催乳素、促黄体激素(LH)和卵泡刺激素(FSH)的基础水平和刺激后水平,另以40名未产妇作对照。结果发现各组血清 LH 和 FSH 的基础水平于妊娠后均无明显改变,促性腺素释放激素刺激后的水平亦无明显改变。但在初次妊娠无论是较早或较晚的两
【New England Journal of Medicine】 January 1987 It is known that primary gestation occurs earlier and protects the body from breast cancer in the future. The United States Musey et al. Speculated that this effect may be caused by prolonged inhibition of prolactin secretion after pregnancy and play a role. To this end, they measured serum prolactin, luteinizing hormone (LH) and serum levels of prolactin (LH) and anti-inflammatory cytokines in 15 women 18 to 23 years of age at first pregnancy and 9 women at first age 29 to 40 years before and after first term pregnancy Follicle-stimulating hormone (FSH) basal level and stimulated level, the other with 40 non-mothers as a control. The results found that the basic level of serum LH and FSH in each group after pregnancy were not significantly changed, gonadotropin-releasing hormone stimulation level did not change significantly. But in the first pregnancy either earlier or later two