作者报导1例因服利福平引起的严重肌病.患者女,44岁,1974年患活动性肺结核,经用异烟肼、利福平治疗16个月而愈.1980年10月症状复发,胸片示新鲜空洞,痰培养结核肝菌(+),给予链霉素、异烟肼、利福平和乙胺丁醇治疗,4周后出现近端肌肉无力、不能站立,无感觉异常、感觉过敏,肌肉疼痛,面肌和眼肌未受累,也无吞咽困难和异常疲劳感等重症肌无力表现.体检:四肢近端肌肉肌力减退伴轻度萎缩,以双下肢为甚;无皮疼,无肌肉压痛 The authors reported a case of severe myopathy caused by rifampicin treatment. Female patient, 44 years old, suffering from active tuberculosis in 1974, with isoniazid, rifampin treatment for 16 months and more. October 1980 symptoms of recurrence , Chest X-ray showed fresh and empty, sputum culture of tuberculosis liver bacteria (+), streptomycin, isoniazid, rifampicin and ethambutol treatment, 4 weeks after the proximal muscle weakness, can not stand, no sensory abnormalities, Sensory hypersensitivity, muscle pain, facial muscles and eye muscles are not involved, nor dysphagia and abnormal fatigue and other symptoms of myasthenia gravis Physical examination: Muscle weakness of the proximal extremities with mild atrophy, to both lower limbs; no skin Pain, no muscle tenderness