【摘 要】
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Dear Editor,Chemotherapy is one of major means for cancer treatments,and many of chemotherapeutic drugs are DNA damaging agents that reduce tumor growth through
【机 构】
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Department of Immunology,Tongji University School of Medicine,Shanghai 200092,China“,”Department of
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Dear Editor,Chemotherapy is one of major means for cancer treatments,and many of chemotherapeutic drugs are DNA damaging agents that reduce tumor growth through triggering cancer cell apoptosis or necrosis.Following DNA damage,ataxia telangiectasia mutated (ATM),a protein kinase,was activated and a cytosolic complex containing ATM,NEMO,RIP1 were formed (Biton and Ashkenazi,2011).
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