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经胃镜确诊90例消化性溃疡(Pu)活动期,按2:1设胃溃灵组60例,雷尼替丁组30例。经治疗6周后.两组的胃镜疗效及胃痛疗效相似,胃溃灵的1年复发率为20%,而雷尼替丁的1年复发率为50%,胃溃灵的远期疗效明显优于雷尼替丁(P<0.01),并随机对胃溃灵组21例患者进行临床实验研究,发现胃溃灵具有抑制十二指肠溃疡(Du)的基础胃酸(BAO),降低Du的胃蛋白酶(PA)活性,促进Pu胃粘膜合成分泌前列腺素E2(PGE2),补充锌元素,有保护胃粘膜屏障的作用。
Gastroscopy diagnosed 90 cases of peptic ulcer (Pu) active phase, according to 2: 1 set up gastric ulceration group 60 cases, ranitidine group 30 cases. After 6 weeks of treatment. Gastroscopy curative effect and gastric pain were similar between the two groups. The one-year recurrence rate of gastric ulcer was 20%, while the one-year relapse rate of ranitidine was 50%. The long-term curative effect of gastric ulcer was superior to that of ranitidine (P <0.01), and randomized to 21 cases of gastric ulcer group clinical experimental study found that stomach ulcer with inhibitory duodenal ulcer (Du) basic gastric acid (BAO), reduce Du pepsin ( PA) activity, and promote Pu gastric mucosal synthesis and secretion of prostaglandin E2 (PGE2), zinc supplements, the role of protecting the gastric mucosal barrier.