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目的 :探讨2型糖尿病患者的血脂水平、血清胎球蛋白A与糖尿病肾病的相关性。方法 :分析2013年1月~2014年12月在我院接受治疗的72例2型糖尿病患者的临床资料,患有2型糖尿病伴糖尿病肾病的病例作为观察组,单纯患有2型糖尿病的病例作为对照组。结果 :两组研究对象HDL-L水平比较,差异具有统计学意义;观察组患者AHSG水平显著高于对照组,差异具有统计学意义;观察组患者炎症因子TNF-α、IL-6水平显著高于对照组,差异具有统计学意义;观察组病例CRP水平显著低于对照组;观察组患者AHSG与HDL-L及TNF-α呈现显著正相关,AHSG与IL-6、CRP呈现显著的负相关。结论 :血清中AHSG与HDL-L及TNF-α呈现正相关,与IL-6、CRP呈现负相关关系。
Objective: To investigate the relationship between serum lipid level, serum fetuin A and diabetic nephropathy in type 2 diabetic patients. Methods: The clinical data of 72 type 2 diabetic patients treated in our hospital from January 2013 to December 2014 were analyzed. Patients with type 2 diabetes mellitus and diabetic nephropathy were selected as the observation group. Patients with type 2 diabetes mellitus As a control group. Results: The levels of HDL-L in the two groups were statistically significant. The level of AHSG in the observation group was significantly higher than that in the control group, and the difference was statistically significant. The levels of TNF-α and IL-6 in the observation group were significantly higher The levels of CRP in observation group were significantly lower than those in control group. There was a significant positive correlation between AHSG, HDL-L and TNF-α in observation group and negative correlation between AHSG, IL-6 and CRP . Conclusion: The serum AHSG is positively correlated with HDL-L and TNF-α, but negatively correlated with IL-6 and CRP.