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目的分析潮州市2008年1月~2014年12月新生儿先天性甲状腺功能减低症(CH)发病率和筛查状况。方法应用时间分辨荧光分析法测定TSH浓度,回顾性方法对其进行分析。结果共筛查新生儿105 373例,检出CH患儿87例,发病率为1/1211。结论新生儿先天性甲状腺功能减低症在新生儿群体中有一定发病率,可以通过新生儿筛查早期发现并干预,提高人口素质。
Objective To analyze the incidence and screening of congenital hypothyroidism (CH) in infants from January 2008 to December 2014 in Chaozhou. Methods The concentration of TSH was determined by time-resolved fluorescence analysis and retrospectively analyzed. Results A total of 105 373 newborns were screened, and 87 children with CH were detected, the incidence rate was 1/1211. Conclusions Neonatal congenital hypothyroidism has a certain morbidity in neonate population. Early detection and intervention can be done through neonatal screening to improve the population quality.