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目的 探讨依托咪酯复合安定用于人工流产的麻醉效果及对病人的影响。方法 选择无痛人工流产 6 0例 ,静脉注射安定 5mg ,3～ 5min后静脉注射依托咪酯 0 3mg/kg ,进行人工流产 ,设置 10 0例对照组观察麻醉效果 ,并对试验组于用药前、用药 2min和手术结束时监测BP、HR、R、SpO2 。结果 实验组镇痛率 10 0 % ,明显高于对照组 2 8% ;宫口松弛率 86 6 7% ,明显高于对照组 15 % ;平均手术时间 4 6 5± 1 2 0min ,明显短于对照组 6 4 9± 1 73min ;人流综合征发生率为 0 ,明显低于对照组 11% ,差异均有非常显著意义 (P<0 0 1)。收缩压和心率于用药前、用药 2min和手术结束时三个时间比较 (方差分析 ) ,差异无显著意义 (P >0 0 5 ) ;而舒张压、呼吸、血氧饱和度三个时间比较 ,差异有非常显著意义 (P <0 0 1)。结论 依托咪酯复合安定静脉麻醉是无痛人工流产的有效方法之一。
Objective To investigate the anesthetic effects of etomidate and diazepam for induced abortion and its impact on patients. Methods Sixty cases of painless induced abortion were selected. Intravenous diazepam (5mg) was given intravenously and etomidate 0 3mg / kg was intravenously injected for induced abortion. The control group was set up to observe the effects of anesthesia. , Medication 2min and the end of surgery to monitor BP, HR, R, SpO2. Results The analgesic rate of the experimental group was 100%, significantly higher than that of the control group (28%). The cervix relaxation rate was 86.67%, which was significantly higher than that of the control group (15%). The mean operative time was 46.5 ± 120 min, The control group was 6 4 9 ± 1 73min. The incidence of flow syndrome was 0, which was significantly lower than that of the control group (11%). The difference was significant (P <0.01). Systolic blood pressure and heart rate before treatment, medication 2min and the end of the operation time comparison (ANOVA), the difference was not significant (P> 0.05); and diastolic blood pressure, respiration, oxygen saturation of three time comparison, The difference was significant (P <0.01). Conclusion Etomidate combined with stable intravenous anesthesia is one of the effective methods for painless induced abortion.