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目的:探讨联合用药在治疗慢性阻塞性肺气肿的临床疗效分析。方法:将60例COPD患者随机分为两组,观察组给予甘氨酸茶碱钠片加复方羟丙茶碱去氯羟嗉胶囊,对照组给予甘氨酸茶碱钠片,观察比较两组病例的临床症状体征和肺功能的改善情况。结果:临床疗效观察组85.6%、对照组71.7%,FEV1观察组总有效率为88.5%、对照组为75.0%,FEV1FVC观察组总有效率为87.1%、对照组为73.3%,而不良反应发生率明显低于对照组。观察组与对照组之间有差异有统计学意义(P<0.05)。结论:联合用药治疗COPD取得了良好的效果。
Objective: To investigate the clinical efficacy of combination therapy in the treatment of chronic obstructive pulmonary emphysema. Methods: Sixty patients with COPD were randomly divided into two groups. The observation group was given glycine theophylline sodium plus compound hydroxypythe theophylline capsules and the control group with glycine theophylline sodium tablets. The clinical symptoms of the two groups were observed and compared Signs and improvements in lung function. Results: The total effective rate in the observation group was 85.6% in the control group, 71.7% in the control group, 88.5% in the FEV1 observation group and 75.0% in the control group. The total effective rate was 87.1% in the FEV1 FVC observation group and 73.3% in the control group The incidence of adverse reactions was significantly lower than the control group. The difference between the observation group and the control group was statistically significant (P <0.05). Conclusion: The combined treatment of COPD has achieved good results.