被放射性治疗毁坏唾液腺的癌症患者,将从转基因技术中获益。美国Dental国家研究院(NIDR)(Bethesda,MD)的科学家利用转入大鼠体内的基因,使不能正常分泌唾液的细胞恢复正常。头颈部癌症患者的放疗经常会损坏位于辐射范围内的唾液腺中分泌唾液的腺泡细胞。一般不分泌唾液的导管细胞却能免遭毁坏。NIDR的研究人员将人的aquaporin—1蛋白基因(hAQP1)导入大鼠导管细胞使这些细胞分泌唾液。Aqnaporins在细胞膜中形成孔隙,使流体 Cancer patients who have been destroyed by salivary glands by radiation therapy will benefit from transgenic technology. Scientists at the National Institute of Dentistry (NIDR) (Bethesda, MD) used genes that were transferred into rats to normalize cells that do not normally secrete saliva. Radiation therapy for head and neck cancer patients often damages salivary acinar cells in the salivary glands located within the radiation range. Catheter cells that do not normally secrete saliva are protected from damage. NIDR researchers introduced the human aquaporin-1 protein gene (hAQP1) into rat ductal cells to make these cells secrete saliva. Aqnaporins form pores in cell membranes, making fluids