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材料及方法:1984年10月6日至1987年7月15日本科住院病人,年龄14～39岁,男3例,女2例,按1972年钩端螺旋体病防治工作座谈会成都会议的诊断及分型标准,5例均属钧端螺旋体病肺弥漫性出血型(钩体病肺大出血型)。在抗菌、解毒、镇静、强心等基础治疗下,大剂量应用654—2,10mg/次,每15分钟静推一次,待呼吸、循环情况改善,肺部湿啰音明显减少或阿托品化后,给药期间酌情延长至1至2小时一次,或者654—2 20～40mg加入10％ G.S100～500ml中缓慢静滴,24小时内654—2总量在50至140mg。
Materials and Methods: Inpatients, aged from 14 to 39 years old, including 3 males and 2 females, were admitted to our hospital from October 6, 1984 to July 15, 1987. According to the diagnosis of the conference on the prevention and treatment of leptospirosis in 1972 in Chengdu And sub-type criteria, 5 cases are Jun spoiled sporadic pulmonary diffuse hemorrhagic (leptospirosis pulmonary hemorrhage). In the antibacterial, detoxification, sedation, cardiac and other basic treatment, high-dose application of 654-2, 10mg / time, every 15 minutes to push once, to be breathing, the circulation improved, lung wet rales significantly reduced or atropine , During administration as appropriate, extended to 1 to 2 hours, or 654-2 20 ~ 40mg added 10% G.S100 ~ 500ml slow intravenous infusion, within 24 hours 654-2 total 50 to 140mg.