目的观察替比夫定(LdT)干预的HBV携带孕妇分娩后用聚乙二醇干扰素α联合阿德福韦抗病毒治疗(CPIA方案)的临床疗效。方法对妊娠晚期用LdT抗病毒干预的高病毒载量的HBV携带孕妇,分娩后根据生物化学、血清学及病毒学的变化,选择ALT≥2倍正常值上限同时伴HBV DNA下降≥3 lg IU/ml和(或)HBeAg滴度下降≥50%者,转换为CPIA方案继续治疗,疗程96周,观察抗病毒疗效及安全性。结
The objective of this 2-yr field trial, with a central composite rotatable design, was to assess and quantify the effects of separation of nitrogen fertilizer a