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目的研究缺血性脑卒中患者血小板糖蛋白Ⅵ(GPⅥ)水平与缺血性脑卒中预后的关系。方法采用流式细胞术测定50例缺血性脑卒中患者发病后24h内的血小板GPⅥ水平,分析其与神经功能缺损程度评分、预后的关系。结果缺血性脑卒中患者血小板GPⅥ含量与病情轻重呈正相关(P<0.01);与病情恢复程度呈负相关(P<0.01)。结论缺血性脑卒中患者血小板GPⅥ含量对患者的近期预后有预测作用。
Objective To investigate the relationship between platelet glycoprotein Ⅵ (GPVI) and the prognosis of ischemic stroke in patients with ischemic stroke. Methods Flow cytometry was used to determine the level of platelet GPVI in 50 ischemic stroke patients within 24 hours after onset, and its relationship with the score of neurological deficit and prognosis were analyzed. Results The platelet GPVI level in ischemic stroke patients was positively correlated with the severity of illness (P <0.01), and negatively correlated with the degree of recovery (P <0.01). Conclusion Platelet GPVI levels in patients with ischemic stroke predict the short-term prognosis of patients.