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目的 :了解我国IPKD—Ⅰ型的流行病学特点及基本状况 ,为进一步研究及治疗此类畸形提供一些参考资料。方法 :1987～ 1992年中国出生缺陷监测网以医院为基础在全国对孕 2 8周至产后 7天的围产儿进行监测 ,对 3 74例IPKD—Ⅰ型患儿进行流行病学分析。结果 :我国IPKD—Ⅰ型的发生率为 0 83 /万 ,发生率呈下降趋势 ,城乡、男女发生率均无显著性差异。 4 4 3 8%的IPKD—Ⅰ型患儿为低体重儿 ,5 0 2 6%的IPKD—Ⅰ型患儿为早产儿。IPKD—Ⅰ型与神经管畸形、直肠肛门畸形和肺发育不全等畸形伴发频率较高。结论 :IPKD—Ⅰ型常以多发性形式出现 ,其围产儿的素质较差。我国IPKD—Ⅰ型发生率呈下降趋势。
OBJECTIVE: To understand the epidemiological characteristics and basic status of IPKD-Ⅰ in our country and to provide some reference materials for further research and treatment of such deformities. Methods: From 1987 to 1992, China National Birth Defective Monitoring Network monitored the perinatal children in China from 28 weeks pregnant to 7 days postpartum on the basis of the hospital, and conducted epidemiological analysis on 3 74 cases of IPKD-Ⅰ children. Results: The incidence of IPKD-Ⅰ type in China was 0 83 per ten thousand, the incidence rate showed a downward trend, and there was no significant difference between urban and rural areas. 4 4 3 8% of children with IPKD-I were of low birth weight and 52.6% of children with IPKD-I were premature infants. IPKD-Ⅰ type and neural tube defects, anorectal malformation and lung hypoplasia and other malformations associated with higher frequency. Conclusion: IPKD-Ⅰ often appear in multiple forms, its quality of perinatal children is poor. The incidence of IPKD-Ⅰ in our country shows a decreasing trend.