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为探讨准分子激光角膜切削术(photorefractivekeratectomy,PRK)后角膜上皮下雾状混浊(haze)的原因及影响因素,对PRK后6个月时屈光度在-1.00~-18.50D的316例(615只眼)近视眼的haze相关因素进行观察和比较。结果:PRK后6个月时haze发生率为44.7%,1级或以上haze为13.3%。haze的发生率及密度随屈光度增高而增加(P<0.0001),也随切削深度的增加而增加(P<0.0001),术前非接触眼压超过18mmHg者,haze的发生率和密度增加(P<0.005),男性较易发生haze(P=0.0001),与年龄呈负相关(P<0.05)。而角膜厚度、术前戴用接触镜及散光对haze的影响不显著。结论:高度近视(>-6.0D)和过深的切削(>80μm)是引起haze的主要原因。术前眼压偏高、年龄偏低对haze也有明显影响。对PRK治疗高度近视应持审
To investigate the causes and influencing factors of corneal haze after corneal laser photocoagulation (PRK), 316 patients with refraction of -1.00 ~ -18.50D at 6 months after PRK (615 eyes) myopia haze related factors were observed and compared. Results: The incidence of haze was 44.7% at 6 months after PRK and 13.3% at grade 1 or above. The incidence and density of haze increased with increasing diopter (P <0.0001), but also with increasing depth of cut (P <0.0001), preoperative non-contact intraocular pressure more than 18mmHg, the incidence of haze and The density was increased (P <0.005), haze was more likely to occur in males (P = 0.0001), and negatively correlated with age (P <0.05). The corneal thickness, preoperative wear contact lenses and astigmatism haze no significant effect. Conclusion: High myopia (> -6.0D) and deep cuts (> 80μm) are the main causes of haze. Preoperative high intraocular pressure, low age haze also have a significant impact. PRK treatment of high myopia should be tried