酶的变化具有反映细胞代谢变异的灵敏特征。动物实验观察到鼠类在致癌过程中,早期表现有 LDH 及其同工酶的改变,以及癌细胞具有 GGT 的活性。在人类肿瘤有关酶的研究还较少,本文对14例食管癌病人进行了组织 LDH 及 CPK 的测定,并对其同工酶作了观察,现报道如下。材料和方法一、食管癌手术标本和处理自肿瘤中心切取癌组织,在癌肿旁1cm处切取癌旁组织,从切端取正常组织,三者均 Changes in enzymes have sensitive characteristics that reflect changes in cellular metabolism. Animal experiments have shown that in the process of carcinogenesis in mice, LDH and its isoenzymes are changed early, and cancer cells have GGT activity. Studies on human tumor-associated enzymes have been relatively rare. In this paper, 14 cases of esophageal cancer patients were measured for LDH and CPK, and their isoenzymes were observed. The report is as follows. Materials and Methods 1. Esophageal cancer surgical specimens and treatment. Cancer tissue was harvested from the center of the tumor. Paracancerous tissue was cut 1 cm away from the tumor and normal tissue was taken from the cut end.