子痫前期为妊娠期特发疾病,是孕产妇和围生儿病率及死亡的主要原因。临床发病多出现在妊娠20周以后,胎盘浅着床和血管内皮受损是本病的主要病理表现,目前对该病的临床处理尚处在早期诊断和对症治疗阶段。因此建立一套可靠的预测方法对存在初产、多胎、妊娠期高血压病史及家族史 Pre-eclampsia is a idiopathic pregnancy disease, maternal and perinatal morbidity and mortality are the main reasons. Clinical onset occurred in more than 20 weeks after pregnancy, placenta asphyxia and vascular endothelial damage is the main pathological manifestations of the disease, the current clinical treatment of the disease is still in the early diagnosis and symptomatic treatment stage. Therefore, to establish a reliable prediction method for the presence of primiparous, multiple births, gestational hypertension history and family history