化学物经皮吸收的定性与定量可通过离体和活体的实验方法而获得。本室早期所建立的离体静式渗透实验模型,经多种化学物研究后发现,离体与活体方法具有高度相关。但由于静式与活体状态相差较远,为此,在静式装置的基础上研制了动式渗透模型。该渗透装置由玻璃渗透室、恒温磁力搅拌器、超级恒温水浴器和全自动电子蠕动泵组成。对七种 Qualitative and quantitative transdermal absorption of chemicals can be obtained by ex vivo and in vivo experimental methods. The chamber in the early establishment of the experimental model of static osmotic infiltration, after a variety of chemical studies found that in vitro and in vivo methods are highly relevant. However, due to the static and living conditions are far apart, for this reason, based on the static device developed dynamic infiltration model. The infiltration device consists of glass infiltration chamber, thermostatic magnetic stirrer, super heated water bath and automatic electronic peristaltic pump. Of seven kinds