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目的探讨硝酸甘油联合卡托普利治疗高血压的临床效果。方法选取高血压急症患者80例,将患者按照随机卡片法,1∶1随机平均分为两组,对照组予以硝酸甘油,观察组予以卡托普利联合硝酸甘油治疗患者。观察1h后降压有效的比例,收缩压与舒张压下降情况,以及不良反应出现情况。结果观察组总体有效率97.5%优于对照组总体有效率80%(P<0.05),观察组收缩压下降舒张压下降与对照组比较显著差异(P<0.05)。两组不良反应比较无显著差异。结论硝酸甘油联合卡托普利治疗高血压能取得较好疗效,具有临床应用价值。
Objective To investigate the clinical effect of nitroglycerin combined with captopril in the treatment of hypertension. Methods Eighty patients with essential hypertension were selected. The patients were randomly divided into two groups according to the random card method, the control group was given nitroglycerin, and the observation group was treated with captopril combined with nitroglycerin. After 1h observed effective antihypertensive ratio, systolic blood pressure and diastolic blood pressure decreased, and the occurrence of adverse reactions. Results The overall effective rate in the observation group was 97.5%, which was significantly better than that in the control group (P <0.05). The decrease of systolic blood pressure in the observation group was significantly lower than that in the control group (P <0.05). There was no significant difference between the two groups. Conclusion Nitroglycerin combined with captopril treatment of hypertension can achieve better effect, with clinical value.