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糖尿病肾病 (ｄｉａｂｅｔｉｃｎｅｐｈｒｏｐａｔｈｙ ,ＤＮ)是糖尿病患者严重的慢性并发症 ,也是导致慢性肾功能不全的常见原因之一。ＤＮ的特征性病理变化是肾小球基底膜增厚及肾小球细胞外基质 (ＥＣＭ)积聚增加所致的系膜区扩张 ,最后导致弥漫性肾小球硬化。在近年的研究
Diabetic nephropathy (DN) is a serious chronic complication of diabetes and is also one of the common causes of chronic renal insufficiency. The characteristic pathological changes of DN are the expansion of the mesangial area caused by the thickening of the glomerular basement membrane and the accumulation of glomerular extracellular matrix (ECM), which eventually leads to diffuse glomerulosclerosis. In recent years research