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目的:探讨子宫瘢痕妊娠的病理免疫组化特点。方法:选取子宫瘢痕妊娠孕妇31例作为观察组及同期妊娠滋养细胞肿瘤患者30例作为对照组。对2组患者切除子宫标准行免疫组化分析,比较CD117、CD34、SMA以及S-100阳性率。结果:观察组患者CD117、CD34、SMA以及S-100阳性率均明显低于对照组,2组比较差异明显,具有统计学意义(P<0.05)。结论:子宫瘢痕妊娠者虽然有滋养细胞的不断生长,但是与妊娠滋养细胞肿瘤之间存在着明显的病理免疫组化差异。
Objective: To investigate the pathological immunohistochemical characteristics of uterine scar pregnancy. Methods: Thirty-one pregnant women with uterine scar pregnancy were selected as the observation group and 30 cases with gestational trophoblastic tumor in the same period as the control group. The uterus was resected immunohistochemically in two groups, and the positive rates of CD117, CD34, SMA and S-100 were compared. Results: The positive rates of CD117, CD34, SMA and S-100 in the observation group were significantly lower than those in the control group. There were significant differences between the two groups (P <0.05). Conclusion: Although uterine scar pregnancy has the continuous growth of trophoblast cells, there is a significant difference in pathological immunohistochemistry with gestational trophoblastic tumor.