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本实验研究铅染毒雄性小鼠血中ALA-D活性与血铅、游离巯基和锌卟啉等的关系。另外一批实验小鼠在铅染毒同时投以铅络合剂EDTA和DM-SA及在体外试验中具有激活ALA-D作用的锌和维生素C观察它们是否在体内能防止铅抑制ALA-D。结果:(1)分别在染毒的第2、4、6、10、
In this study, the relationship between ALA-D activity and blood lead, free sulfhydryl and zinc porphyrin in blood of lead-poisoned mice was studied. Another group of experimental mice administered lead EDTA and DM-SA at the same time as lead poisoning and zinc and vitamin C with ALA-D activation in vitro test whether they can prevent lead inhibition of ALA-D . Results: (1) In the exposure of the first 2,4,6,10,