进行性半侧颜面萎缩是一类以半侧面部萎缩为主要表现的疾病,由于病因及发病机制尚不明确,临床工作中缺乏有效的治疗指导。近年来,众多学者对其发病机制进行了大量研究,取得了一些进展。本文从神经系统、免疫系统以及感染等方面,就进行性半侧颜面萎缩的病因及发病机制作一综述。 Progressive hemivengeal atrophy is a type of half-facial atrophy as the main manifestation of the disease, due to etiology and pathogenesis is not clear, the lack of effective clinical treatment guidelines. In recent years, many scholars have done a lot of research on its pathogenesis and made some progress. This article reviews the etiology and pathogenesis of progressive hemifacial atrophy from the nervous system, immune system and infection.