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目的:对脑卒中和轻中型颅脑损伤的失语症患者行进高压氧治疗,探讨高压氧对失语症患者语言功能的影响及康复机制。方法:将40例失语症患者按入组次序分为治疗组和对照组。治疗组在常规治疗的基础上于发病7d后进行高压氧治疗,15d1个疗程,疗程之间休息3d,共3个疗程,运用语言障碍诊治仪ZM2·1检测每一疗程患者的语言功能并与对照组比较,观察语言功能的变化。结果:治疗组与对照组各疗程疗效比较:第一疗程后各项语言功能均有所提高,但与对照组比较差异无统计学意义(P>0·05);第二疗程后,除听读字亚项外,治疗组10个亚项语言功能明显高于对照组(P<0·05),第三疗程后11个亚项语言功能均明显高于对照组(P<0·05)。治疗组各疗程前后疗效比较:每1疗程结束后各项语言水平均有提高,其中第一、第二疗程后复杂指令、表达语音和表达语义3个亚项明显改善(P<0·05)。结论:高压氧可能通过促进神经细胞的功能恢复和自我修复,减轻脑缺血再灌注,从而促进失语症患者语言功能的康复,这种作用在第一及第二疗程表现最佳,其康复作用表现为加快其原有恢复的速度,并不针对于某些语言功能。
OBJECTIVE: To investigate the effect of hyperbaric oxygen on the speech function of aphasia patients and the mechanism of rehabilitation after atropisophageal stroke in patients with stroke and light-medium traumatic brain injury. Methods: 40 cases of aphasia patients were divided into treatment group and control group according to the order of the group. On the basis of routine treatment, the patients in the treatment group were treated with hyperbaric oxygen for 7 days after the onset of disease, 15 days and 1 week after treatment. The patients in the treatment group were rested for 3 days for three courses of treatment. The language function of each course of treatment was detected by ZM2.1 The control group, observe the changes in language function. Results: The treatment group and control group compared the efficacy of the treatment: the first course of the language features have increased, but compared with the control group, the difference was not statistically significant (P> 0.05); after the second course of treatment, Reading sub-items, the linguistic functions of the 10 sub-items in the treatment group were significantly higher than those in the control group (P <0.05). The language features of the 11 sub-items in the treatment group were significantly higher than those in the control group (P <0.05) . The treatment group before and after treatment compared the efficacy of each session after the end of each language levels have improved, including the first and second courses after the complex instructions, speech and expression of semantic expression of three sub-significantly improved (P <0.05) . CONCLUSION: Hyperbaric oxygen may promote the rehabilitation of speech function of patients with aphasia by promoting functional recovery and self-repair of nerve cells and relieving cerebral ischemia-reperfusion. This effect is the best in the first and second courses of treatment, and its rehabilitation It appears to speed up its original recovery and is not specific to certain language features.