以干扰素为基础的抗病毒治疗儿童慢性乙型及丙型肝炎已是共识,且取得了较好的疗效。但干扰素、病毒唑治疗中可引起不同程度不良反应,一些不良反应会影响儿童用药的依从性及疗程的完成,从而影响抗病毒疗效[1-3]。因此,充分了解抗病毒治疗药物的不良反应、密切观察及早发现不良反应并采取恰当的处理措施是提高抗病毒疗效的关键之一。 Interferon-based antiviral treatment of children with chronic hepatitis B and C has been the consensus, and achieved good results. However, interferon and ribavirin treatment can cause different degrees of adverse reactions, some adverse reactions will affect the compliance of children with medication and the completion of the course of treatment, thus affecting the antiviral effect [1-3]. Therefore, to fully understand the adverse effects of antiviral drugs, to closely observe the early detection of adverse reactions and take appropriate measures to improve anti-viral efficacy is one of the keys.