肝昏迷是严重肝脏疾病(暴发型病毒性肝炎与中毒性肝炎、失代偿性肝硬化等)最常见的症群之一,病死率很高。近年来,各国学者对本病的治疗作了很多研究,曾先后试用了大剂量肾上腺皮质激素、换血法、换血浆法、高压氧疗法、肝素疗法、血液或腹膜透析、体外异体(猪、小牛、狒狒等)肝灌洗、交叉循环(人～人或人～灵长类)、人工肝脏、肝脏移植、左旋多巴疗法等。 Hepatic coma is one of the most common syndromes of severe liver disease (fulminant viral hepatitis and toxic hepatitis, decompensated cirrhosis, etc.) and has a high case fatality rate. In recent years, scholars from various countries have done a lot of researches on the treatment of this disease. They have tried high-dose adrenocorticotropic hormone, blood exchange, plasma exchange, hyperbaric oxygen therapy, heparin therapy, blood or peritoneal dialysis, in vitro allogeneic Cattle, baboons, etc.) Liver lavage, cross-circulation (human ~ human or human primate), artificial liver, liver transplantation, levodopa therapy.