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目的研究血清前白蛋白(PA)和异柠檬酸脱氢酶(ICDH)联合检测对早期肝损害的意义。方法分别检测200例急性乙型肝炎(乙肝)患者PA、ICDH、谷丙转氨酶(ALT)、白蛋白(ALB)水平,分析结果。结果 PA低于参考值161例,ICDH高于参考值132例,ALT高于参考值83例,ALB低于参考值11例。结论急性乙肝时PA降低比ALB出现更早,ICDH升高比ALT出现更早。所以,PA和ICDH对早期肝损害诊断比ALT和ALB敏感。
Objective To study the significance of combined detection of serum prealbumin (PA) and isocitrate dehydrogenase (ICDH) on early liver damage. Methods The levels of PA, ICDH, ALT and ALB in 200 patients with acute hepatitis B were detected respectively. The results were analyzed. Results PA was lower than the reference value of 161 cases, ICDH higher than the reference value of 132 cases, ALT higher than the reference value of 83 cases, ALB lower than the reference value of 11 cases. Conclusions The PA reduction in acute hepatitis B is earlier than that in ALB, and the ICDH is higher than that in ALT. Therefore, PA and ICDH are more sensitive to diagnosis of early liver damage than ALT and ALB.