患者。男,4 8岁,工人。因全身起红褐色斑、丘疹30年,微痒。患者15岁时前额起一豆大红斑,逐渐增多,并先后累及双手背,双上肢、腹部,皮损散在分布。2 0岁时皮损明显增多。曾多次到医院就诊,诊断不明,外擦药膏(不详)未见效果。否认有家族史。系统检查无异常,皮肤科检查:面部左侧颞 patient. Male, 48 years old, worker. Due to reddish brown body spots, pimples for 30 years, itching slightly. At the age of 15, the patient developed a large erythema of erythrocytes from his forehead, which gradually increased. His hands, back and legs, upper extremities, abdomen and skin lesions spread successively. 20 years old skin lesions increased significantly. Have repeatedly to the hospital for treatment, diagnosis is unknown, outside rub ointment (unknown) no effect. Denied family history. No abnormalities in the system check, dermatology examination: temporal left facial