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缺血再灌注损伤(Ischemia Reperfusion Injury,IRI)是指遭受一定时间缺血的组织恢复血供后,组织损伤程度加重的病理现象。肾脏是对缺血以及缺血再灌注非常敏感的器官,肾IRI与诸多肾脏疾病的发病有密切关联,是造成缺血性急性肾功能衰竭和影响移植肾早期功能恢复的主要因素。研究
Ischemia Reperfusion Injury (IRI) refers to the pathological phenomenon that tissue damage is exacerbated after blood supply to the tissue subjected to ischemia for a certain period of time. Kidney is an organ that is very sensitive to ischemia and ischemia-reperfusion. Renal IRI is closely related to the pathogenesis of many kidney diseases. It is the main factor that causes ischemic acute renal failure and affects the early functional recovery of renal allografts. the study