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近年来发现一类能激活T淋巴细胞比一般抗原多达数千倍的抗原,被称为“超抗原”,主要是一些细菌的毒素和逆转录病毒基因的产物。研究表明,超抗原能够以与普通抗原不同的方式,与主要组织相容性复合体(majorhlstocompatlbllitycomplex,MHC)I类分子结合,作用于T细胞受体(T
In recent years, it has been discovered that a class of antigens that activate T lymphocytes up to several thousand times more than normal antigens are called “superantigens” and are mainly products of bacterial toxins and retroviral genes. Studies have shown that superantigen can bind to major histocompatibility complex (MHC) class I molecules in a manner different from common antigens and act on T cell receptors (T